PSMA I&T

Precursor for radiometal-labelled PSMA I&T
PSMA: prostate-specific membrane antigen

Structurformel

Research Chemical

Molar Mass: 1498,37
C63H92IN11O23
[2192281-54-0]

Colourless to off-white solid

Purity: > 95 %

Certificates:
  • CoA
  • ;
  • 1H NMR spectrum (identity)
  • ;
  • HPLC (Purity)

Chemical Name: Sequence: Glu-CO-Lys[(Sub)DLys-DPhe-DTyr(3I)-DOTAGA]

Literature:
  1. Baum R.P. et al. 177Lu-Labeled Prostate-Specific Membrane Antigen Radioligand Therapy of Metastatic Castration-Resistant Prostate Cancer: Safety and Efficacy. J. Nucl. Med. 2016, 57, 1006-1013.
  2. Eiber M. et al. Systemic Radioligand Therapy with (177)Lu Labeled Prostate Specific Membrane Antigen Ligand for Imaging and Therapy in Patients with Metastatic Castration Resistant Prostate Cancer. J. Nucl. Med., 2016, 57(supplement 2): p. 61-61.
  3. Schottelius M. et al. [111In] PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery. EJNMMI Res. 2015, 5, 68.
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