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ABX  advanced biochemical compounds   

Product Order number / Unit

105 Mannose Triflate PLUS, ultra pure 105.0020: 20 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for [18F]FDG
Manufactured according to GMP requirements for APIs (ICH Q7) Pharmaceutical grade (EDMF/DMF)
Molar Mass: 480.37
Colourless or nearly colourless crystals packaged in 2 ml dark glass vials (DIN 2R) with teflon-faced rubber stoppers, tear-off crimp caps, argon flushed.
Melting range 119 - 122 degC. Soluble in acetonitrile, acetone, DMSO, methanol. Insoluble in aqueous media.
Purity: > 99 %
CoA with 1H, 19F NMR, and IR spectra, specific optical rotation and melting point (identity), HPLC, GC, and thermogravimetry (chemical purity); testing for bacterial endotoxines and sterility (microbiological purity)
Chemical Name:
CA index name: beta-D-mannopyranose, 1,3,4,6-tetraacetate 2-(trifluoromethane-sulfonate)
TATM; mannose triflate; 1,3,4,6-tetra-O-acetyl-2-O-trifluoro-methanesulfonyl-beta-D-mannopyranose
Hamacher K. et al. Efficient stereospecific synthesis of no-carrier-added 2-[18F]fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution. J. Nucl. Med. 1986, 27, 235-238.
Padgett H. et al. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Appl. Radiat. Isot. 1989, 40, 433-445.
Pavliak V. et al. A short synthesis of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-beta-D-glucopyranose and the corresponding α-glucosyl chloride from D-mannose. Carbohydr. Res. 1991, 210, 333-337.
Chirakal R. Traces of fluorine containing impurities in the mannose triflate and their adverse effect on the radiochemical yield of 2-[18F]FDG. XIIth ISRC. Uppsala, Sweden 1997, 214-216.
date of product catalogue issue: 10 May 2017


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