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ABX  advanced biochemical compounds   

Product Order number / Unit

1926 FFNP precursor 1926.0002: 2 mg per vial
1926.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for [18F]FFNP
([18F]Fluoro furanyl norprogesterone)
Molar Mass: 504.59
Colourless to off-white solid packaged in dark glass screw cap vials.
Purity: > 95 %
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 19-Norpregn-4-ene-3,20-dione, 16,17-[[(R)-2-furanylmethylene]bis(oxy)]-21-[(methylsulfonyl)oxy]-, (16)-alpha
16α,17α-[(R)-(1'-α-Furylmethylidene)dioxy]-21[(methyl)sulfonyl]oxy-19-norpregn-4-ene-3,20-dione; [18F]FFNP precursor
Zhou D. et al. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16α-[18F]fluoroestradiol (FES), [18F]fluoro furanylnorprogesterone (FFNP), and 16β-[18F]fluoro-5α-dihydrotestosterone (FDHT) as radiopharmaceuticals. J. Label. Compd. Radiopharm. 2014, 5, 371-377.
Vijaykumar D. et al. An Efficient Route for the Preparation of a 21-Fluoro Progestin-16alpha,17alpha-Dioxolane, a High-Affinity Ligand for PET Imaging of the Progesterone Receptor. J. Org. Chem. 2002, 67, 4904-4910.
Buckman B.O. et al. Fluorine-18-Labeled Progestin 16alpha,17alpha-Dioxolanes: Development of High-Affinity Ligands for the Progesterone Receptor with High in Vivo Target Site Selectivity. J. Med. Chem. 1995, 38, 328-337.
date of product catalogue issue: 10 May 2017


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