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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

2060 (S)-(-)-Normethylcarbamoyl-GR 103545 2060.0001: 1 mg per vial
2060.0003: 3 mg per vial
2060.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Precursor for (R)-(-)-[11C]-GR 103545
Molar Mass: 356.29
C17H23Cl2N3O
[260992-21-0]
Yellowish oil packaged in dark glass crimp cap vials.
Purity: > 95 %
Certificates:
CoA; 1H and 13C NMR spectra
Chemical Name:
CA index name: Ethanone, 2-(3,4-dichlorophenyl)-1-[(2S)-2-(1-pyrrolidinylmethyl)-1-piperazinyl]-
Synonymes:
(2S)-2-(3,4-Dichlorophenyl)-1-(2-pyrrolidin-1-ylmethyl-piperazine-1-yl)-ethanon; (2S)-1-[(3,4-Dichlorophenyl)acetyl]-2-(1-pyrrolidinymethyl)piperazine
Literature:
Ravert H.T. et al. [11C]-GR 89696, a potent kappa opiate receptor radioligand; in vivo binding of the R and S enantiomers. Nuc. Med. Biol. 2002, 29, 47-53.
Talbot P.S. et al. 11C-GR 103545, a Radiotracer for Imaging κ-Opioid Receptors In Vivo with PET: Synthesis and Evaluation in Baboons. J. Nucl. Med. 2005, 46, 484-494.
Naylor A. et al. A Potent New class of κ-Receptor Agonist: 4-Substituted 1-(Arylacetyl)-2-[(dialkylamino)methyl]piperazines. J. Med. Chem. 1993, 36, 2075-2083.
Schoultz B.W. et al. A New Method for Radiosynthesis of 11C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [11C]GR 103545. The Open Med. Chem. J. 2008, 2 ,72-74.
Nabulsi N.B. et al. [11C]GR103545: novel one-pot radiosynthesis with high specific activity. Nucl. Med. Biol. 2011, 38, 215-21.
date of product catalogue issue: 24 February 2017

 
 
 

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