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Catalogue Number |
Product | Order number / Unit |
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2061 | (R)-(+)-Normethylcarbamoyl-GR 103545 |
2061.0001: 1 mg per vial 2061.0003: 3 mg per vial 2061.0010: 10 mg per vial Please inquire for customized filling and bulk quantities. ![]() |
Precursor for (S)-(+)-[11C]-GR 103545
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Molar Mass: 356.29 | ||
C17H23Cl2N3O | ||
[199470-02-5] | ||
Yellowish oil packaged in dark glass crimp cap vials. | ||
Purity: > 95 % | ||
Certificates:
CoA; 1H and 13C NMR spectra |
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Chemical Name: CA index name: Piperazine, 1-[(3,4-dichlorophenyl)acetyl]-2-(1-pyrrolidinylmethyl)-, (2R) |
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Synonymes: (2R)-2-(3,4-Dichlorophenyl)-1-(2-pyrrolidin-1-ylmethyl-piperazine-1-yl)-ethanon; (2R)-1-[(3,4-Dichlorophenyl)acetyl]-2-(1-pyrrolidinymethyl)piperazine |
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Literature: Ravert H.T. et al. [11C]-GR 89696, a potent kappa opiate receptor radioligand; in vivo binding of the R and S enantiomers. Nuc. Med. Biol. 2002, 29, 47-53. |
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Talbot P.S. et al. 11C-GR 103545, a Radiotracer for Imaging κ-Opioid Receptors In Vivo with PET: Synthesis and Evaluation in Baboons. J. Nucl. Med. 2005, 46, 484-494. | ||
Naylor A. et al. A Potent New class of κ-Receptor Agonist: 4-Substituted 1-(Arylacetyl)-2-[(dialkylamino)methyl]piperazines. J. Med. Chem. 1993, 36, 2075-2083. | ||
Schoultz B.W. et al. A New Method for Radiosynthesis of 11C-Labeled Carbamate Groups and its Application for a Highly Efficient Synthesis of the Kappa-Opioid Receptor Tracer [11C]GR 103545. The Open Med. Chem. J. 2008, 2 ,72-74. | ||
date of product catalogue issue: 10 May 2017 |