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ABX  advanced biochemical compounds   

Product Order number / Unit

2450 (S)-FPSPPA 2450.0100: 100 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for (S)-[11C]-Methyl-FPSPPA
2-[(2-Fluorophenyl)methyl]-3-(2-fluorospiro[4,5-dihydrothieno [2,3-c]pyran-7,40-piperidine]-10-yl)propanamide
Molar Mass: 406.49
White solid packaged in dark glass vials.
Purity: > 95 %
CoA; 1H NMR spectrum
Chemical Name:
Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]-1-propanamide, 2'-fluoro-α-[(2-fluorophenyl)methyl]-4',5'-dihydro-, (αS)-
(2S)-2-[(2-Fluorophenyl)methyl]-3-(2-fluorospiro[4,5-dihydrothieno [2,3-c]pyran-7,40-piperidine]-10-yl)propanamide
Pike V. et al. Synthesis and Evaluation of Radioligands for Imaging Brain Nociceptin/Orphanin FQ Peptide (NOP) Receptors with Positron Emission Tomography, J. Med. Chem. 2011, 54, 2687-2700.
Pedregal C. et al. Development of LC-MS/MS-Based Receptor Occupancy Tracers and Positron Emission Tomography Radioligands for the Nociceptin/Orphanin FQ (NOP) Receptor, J. Med. Chem. 2012, 55, 4955-4967.
Kimura Y. et al. Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors, J. Nucl. Med. 2011, 52, 1638-1645.
date of product catalogue issue: 10 May 2017


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