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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

3354 (-)-Flubatine precursor (GMP)
Please inquire for customized filling and bulk quantities.

 
Precursor for (-)-[18F]Flubatine
Manufactured according to GMP requirements for APIs for use in clinical trials (ICH Q7 chapter 19)
Molar Mass: 473.39
C20H32IN3O2
[1421915-93-6]
White to yellowish solid packaged in dark glass vials.
Purity:
Certificates:
CoA with NMR and IR spectra, ESI-MS (identity); optical rotation; HPLC (purity); GC (residual solvents)
Chemical Name:
5-((1R, 5S, 6S)-8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide
Synonymes:
ABX088, (-)-Flubatine precursor; (-)-NCFHEB precursor; (-)-5-(8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide
Literature:
Präkursorverbindungen für die Radiosynthese von [18F]Norchlor-fluor-homoepibatidin. Patent DE 2011080118062700
Brust P. et al. In vivo measurement of nicotinic acetylcholine receptors with [18F]norchloro-fluoro-homoepibatidine. Synapse 2008, 62, 205-218.
Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine (NCFHEB) - a promising radioligand for neuroimaging nicotinic acetylcholine receptors with PET. Eur. Neuropsychopharmacol. 2008, 18, 222-229.
Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro. Farmaco, 2004, 59, 785-792.
date of product catalogue issue: 24 February 2017

 
 
 

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