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ABX  advanced biochemical compounds   

Product Order number / Unit

3370 Nifene 3370.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Reference standard for [18F]Nifene
Molar Mass: 230.67
C10H11FN2O ⋅ HCl
[912843-69-7] (free base)
Slightly purple solid packaged in dark glass screw cap vials.
Purity: > 95 %
CoA; 1H and 19F NMR spectra
Chemical Name:
Pyridine, 3-[[(2S)-2,5-dihydro-1H-pyrrol-2-yl]methoxy]-2-fluoro-, hydrochloride salt
3-(2,5-Dihydro-1H-pyrrol-2-ylmethoxy)-2-fluoro-pyridine hydrochloride
Mukherjee J. et al. Effect of acetylcholinesterase inhibitors on the binding of nicotinic α4β2 receptor PET radiotracer, (18)F-nifene: A measure of acetylcholine competition. Synapse 2007, 61, 29-36.
Pichika R. et al. Nicotinic α4beta2 receptor imaging agents. Part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate. Nucl. Med. Biol. 2006, 33, 295-304.
date of product catalogue issue: 10 May 2017


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