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ABX  advanced biochemical compounds   

Product Order number / Unit

3520 Desmethyl-GR 205171 Dihydrochloride 3520.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for [11C]GR 205171
Molar Mass: 491.34
C20H21F3N6O ⋅ 2 HCl
Yellowish solid packaged in dark glass crimp cap vials.
Purity: > 95 %
CoA; 1H, 13C and 19F NMR spectra
Chemical Name:
CA index name: Phenol, 2-[[[(2S,3S)-2-phenyl-3-piperidinyl]-amino]methyl]-4-[5-(trifluoromethyl)-1H-tetrazol-1-yl]-, dihydrochloride
Phenol, 2-[[(2-phenyl-3-piperidinyl)amino]methyl]-4-[5-(trifluoromethyl)-1H-tetrazol-1-yl]-, dihydrochloride, (2S-cis)-;
Bergström M. et al. Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 2000, 39, 664-670.
Zamuner S. et al. Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach Nucl. Med. Biol. 2002, 29, 115-123.
Bergström M. et al. A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11C]-L-DOPA and Pittsburgh Compound-B. Neuroimage 2006, 33, 588-598.
date of product catalogue issue: 24 February 2017


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