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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

3720 Desmethyl-MK-8278 3720.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Precursor for [11C]MK-8278
Molar Mass: 386.48
C22H30N2O4
[879368-41-9]
Colourless to off-white foam/solid packaged in dark glass screw cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum; HPLC
Chemical Name:
Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-carboxamide, 5'-hydroxy-N-methyl-3'-oxo-N-[2-(1-piperidinyl)ethyl]-, (1alpha,4beta)-
Synonymes:
trans-5'-Hydroxy-3'-oxo-N-methyl-N-(2-piperidin-1-ylethyl)-spiro[cyclohexane-1,1'-(3'-H)-isobenzofuran]-4-carboxamide; [11C]MK-8278 precursor
Literature:
Van Laere K. J. et al. 11C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists. J. Nucl. Med. 2014, 55, 65-72.
Hamill T. G. et al. Inverse Agonist Histamine H3 Receptor PET Tracers Labelled With Carbon-11 or Fluorine-18. Synapse 2009, 63, 1122-1132.
date of product catalogue issue: 24 February 2017

 
 
 

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