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ABX  advanced biochemical compounds   

Product Order number / Unit

4210 Altropane 4210.0001: 1 mg per vial
4210.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Reference standard for [11C]Altropane
Reference standard for [*I]Altropane

Molar Mass: 429.27
Colourless to orange solid packaged in dark glass screw cap vials.
Purity: > 95 %
CoA; 1H and 19F NMR spectra
Chemical Name:
CA index name: 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-fluorophenyl)-8-[(2E)-3-iodo-2-propenyl]-, methyl ester, (1R,2S,3S,5S)-
(E)-N-(1-Iodoprop-1-en-3-yl)-3-β-(4-fluorophenyl)-nortropane-2-β-carboxylic acid methyl ester; (E)-N-(3-Iodoprop-2-enyl)-2β-carbomethoxy-3β-(4-fluorophenyl)-nortropane; 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(4-fluorophenyl)-8-(3-iodo-2-propenyl)-, methyl ester, [1R-[1a,2a,3a,5a,8(E)]]-; IACFT
Fischman A.J. et al. [11C,127I] Altropane: a highly selective ligand for PET imaging of dopamine transporter sites. Synapse 2001, 39, 332-342.
Elmaleh D.J. et al. Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites. J. Nucl. Med. 1996, 37, 1197-1202.
Madras B.K. et al. Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse 1998, 29, 93-104. II. Distribution to dopamine-rich regions of primate brain. Synapse 1998, 29, 105-115 III. Human dopamine tranporter in postmortem normal and Parkinsons brain. Synapse 1998, 29, 116-127.
date of product catalogue issue: 10 May 2017


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