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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

4330 AFM standard 4330.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Reference standard for [11C]AFM and [18F]AFM
([11C]2-(2-(Dimethylaminomethyl)phenylthio)-5-fluoromethylphenylamine)
Molar Mass: 290.40 (free base)
C16H19FN2S ⋅ x HCl
[627490-40-8] (free base)
Colourless solid packaged in dark glass screw cap vials.
Purity: > 90 %
Certificates:
CoA; 1H and 19F NMR spectra
Chemical Name:
Benzenemethanamine, 2-[[2-amino-4-(fluoromethyl)phenyl]thio]-N,N-dimethyl-, hydrochloride salt
Synonymes:
2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluoromethyl-phenylamine hydrochloride salt
Literature:
Huang Y. et al. Comparative Evaluation in Nonhuman Primates of Five PET Radiotracers for Imaging the Serotonin Transporters: [11C]McN 5652, [11C]ADAM, [11C]DASB, [11C]DAPA, and [11C]AFM. J. Cereb. Blood Flow Metab. 2002, 22, 1377-1398.
Huang Y. et al. Fluorinated Analogues of ADAM as New PET Radioligands for the Serotonin Transporter : Synthesis and Pharmacological Evaluation. J. Labelled Compd. Radiopharm. 2001, 44, Suppl. 1, S18-S20.
Oya S. et al. New PET Imaging Agent for the Serotonin Transporter: [18F]ACF (2-[(2-Amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenemethanamine). J. Med. Chem. 2002, 45, 4716-23.
date of product catalogue issue: 10 May 2017

 
 
 

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