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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

4500 Norbinaltorphimine dihydrochloride 4500.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 

Highly selective kappa opioid receptor antagonist
Molar Mass: 734.71
C40H43N3O6 ⋅ 2 HCl
[113158-34-2]
[105618-26-6] (free base)
Tan solid packaged in dark glass screw cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 4,8:11,15-Dimethano-20H-bisbenzofuro[2,3-a:3′,2′-i]dipyrido[4,3-b:3′,4′-h]carbazole-1,8a,10a,18-tetrol, 7,12-bis(cyclopropylmethyl)-5,6,7,8,9,10,11,12,13,14,19a,20b-dodecahydro-, hydrochloride (1:2), (4bS,8R,8aS,10aS,11R,14aS,19aR,20bR)-
Synonymes:
NorBNI; N-Desmethylbinaltorphimine; N-Demethylbinaltorphimine dihydrochloride
Literature:
Portoghese P.S. et al. Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists. Life Sci. 1987, 40, 1287-1292.
Takemori A.E. et al. Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays. J. Pharmacol. Exp. Ther. 1988, 246, 255-258.
Lambert P.D. et al. The effect of central blockade of kappa-opioid receptors on neuropeptide Y-induced feeding in the rat. Brain Res. 1993, 629, 146-148.
date of product catalogue issue: 24 February 2017

 
 
 

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