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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

5166 O-Desmethyl Astemizole
Please inquire for customized filling and bulk quantities.

 
Precursor for [11C]Astemizole and [18F]Fluoroethyl-astemizole
Molar Mass: 444.54
C27H29FN4O
[73736-50-2]
Colourless to off-white solid packaged in dark glass screw cap vials or dark glass crimp cap vials.
Purity: > 95 %
Certificates:
CoA; 1H and 19F NMR spectra
Chemical Name:
4-[2-[4-[[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]phenol
Synonymes:
O-desmethylastemizole; 4-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-ylamino]-piperidin-1-yl}-ethyl)-phenol; [11C]Astemizole precursor; [18F]Astemizole precursor
Literature:
Riss P. J. et al. Radiosynthesis and characterization of astemizole derivatives as lead compounds toward PET imaging of τ-pathology. Med. Chem. Commun. 2013, 4, 852-855.
Cai L. et al. Synthesis of [11C]astemizole as a lead candidate radioligand for imaging brain neurofibrillary tangles. Neuroimage 2010, 52, Supplement 1, S152-S153
date of product catalogue issue: 24 February 2017

 
 
 

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