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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

5200 Desmethyl-PD 153035 5200.0001: 1 mg per vial
Please inquire for customized filling and bulk quantities.

 
Precursor for [Methoxy-11C]PD 153035
Potent and specific inhibitor of the EFG receptor tyrosine kinase
Molar Mass: 346.18
C15H12BrN3O2
[295330-61-9]
Yellowish solid packaged in dark glass crimp cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 6-Quinazolinol, 4-[(3-bromophenyl)amino]-7-methoxy-
Synonymes:
4-Quinazolinamine, N-(3-bromphenyl)-6-hydroxy-7-methoxy-; 4-(3-Bromophenylamino)-7-methoxyquinazolin-6-ol; 4-[(3-Bromophenyl)amino]-6-hydroxy-7-methoxyquinazoline
Literature:
Fredriksson A. et al. In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants Life Sci. 1999, 65, 165-174.
Johnström P. et al. Synthesis of [Methoxy-11C]PD153035, a Selective EGF Receptor Tyrosine Kinase Inhibitor J. Labelled Compd. Radiopharm. 1998, 41, 623-629.
Gibson K.H. et al. Epidermal growth factor receptor tyrosine kinase: Structure-activity relationships and antitumour activity of novel quinazolines Bioorg. Med. Chem. Lett. 1997, 7, 2723-2728.
date of product catalogue issue: 10 May 2017

 
 
 

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