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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

5210 PD 153035 5210.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Reference standard for [Methoxy-11C]PD 153035
Potent and specific inhibitor of the EFG receptor tyrosine kinase
Molar Mass: 360.21
C16H14BrN3O2
[153436-54-5]
Yellowish solid packaged in dark glass screw cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 4-Quinazolinamine, N-(3-bromphenyl)-6,7-dimethoxy-
Synonymes:
4-(3-Bromphenylamino)-6,7-bis(methoxy)quinazoline; 4-(3-Bromphenylamino)-6,7-dimethylquinazoline; AG 1517; NSC 669364; SU 5271; WHI-P 79
Literature:
Fredriksson A. et al. In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants Life Sci. 1999, 65, 165-174.
Johnström P. et al. Synthesis of [Methoxy-11C]PD153035, a Selective EGF Receptor Tyrosine Kinase Inhibitor J. Labelled Compd. Radiopharm. 1998, 41, 623-629.
Gibson K.H. et al. Epidermal growth factor receptor tyrosine kinase: Structure-activity relationships and antitumour activity of novel quinazolines Bioorg. Med. Chem. Lett. 1997, 7, 2723-2728.
date of product catalogue issue: 24 February 2017

 
 
 

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