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ABX  advanced biochemical compounds   

Product Order number / Unit

7015 SGMIB Precursor 7015.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for [131I]SGMIB
N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate
Molar Mass: 653.31
Colourless to off-white solid/foam packaged in dark glass screw cap vials.
Purity: > 95 %
CoA; 1H NMR spectrum
Chemical Name:
CA index name: Carbamic acid, [[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl][[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2-(trimethylstannyl)phenyl]methyl]-, 1,1-dimethylethyl ester
N-Succinimidyl 4-[N1,N2-Bis(tert-butyloxycarbonyl)guanidinomethyl]-3-(trimethylstannyl)benzoate; Benzoic acid, 4-[[[(1,1-dimethylethoxy)carbonyl][[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]amino]methyl]-3-(trimethylstannyl)-, 2,5-dioxo-1-pyrrolidinyl ester; SGMIB Precursor
Vaidyanathan G. et al. A Polar Substituent-Containing Acylation Agent for the Radioiodination of Internalizing Monoclonal Antibodies: N-Succinimidyl 4-Guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB). Bioconjugate Chem. 2001, 12 ,428-438.
Vaidyanathan G. et al. Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides. Nature Protocols 2007, 2, 282-286.
date of product catalogue issue: 10 May 2017


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