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ABX  advanced biochemical compounds   

Product Order number / Unit

7510 S-(-)-IBZM 7510.0001: 1 mg per vial
7510.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Reference standard for S-(-)-[*I]IBZM
Precursor for S-(-)-[123/125I]IBZM
Molar Mass: 404.24
Dark yellow oil packaged in dark glass crimp cap vials (7510.0001) or screw cap vials (7510.0010).
Purity: > 95 %
CoA; 1H NMR spectrum
Chemical Name:
CA index name: Benzamide, N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxy-
Iodobenzamide, (S)-(-)-3-Iodo-2-hydroxy-6-methoxy-N[(1-ethyl-2-pyrrolidinyl)methyl]benzamide
Kung H.F. et al. Dopamine D-2 receptor Imaging Radiopharmaceuticals: Synthesis, Radiolabeling and in Vitro binding of R(+)- and S(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide. J. Med. Chem. 1988, 31, 1039-1043.
Cordes M. et al. Initial experience with SPECT examinations using [123I]IBZM as a D2-dopamine receptor antagonist in Parkinson′s disease. Eur. J. Radiol. 1991, 12, 182.
Innis R.B. et al. Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2receptor in nonhuman primates. Synapse 1992, 10, 177.
Ichise M. et al. Iodine-123-IBZM dopamine D2receptor and technetium -99 m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington′s disease J. Nucl. Med. 1993, 34, 1274.
date of product catalogue issue: 10 May 2017


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