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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

9705 Lu-DOTA-TOC
Please inquire for customized filling and bulk quantities.

 
Reference standard for 177Lu-DOTA-TOC
Molar Mass: 1593.58 (net peptide)
C65H89LuN14O18S2
[321835-55-6] ([177Lu]-DOTA-TOC)
Colourless to off-white solid packaged in dark glass screw cap vials.
Purity: ≥ 95 %
Certificates:
CoA; MS (identity); HPLC (purity)
Chemical Name:
Sequence: DOTA(Lu)-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide.
Synonymes:
natLu-Edotreotide; natLu-SMT487; natLu-DOTA-[Tyr3]octreotide; Lutetium-177Lu, [N-[2-[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-; Lutetium-177Lu, [N-[[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl]acetyl-κO]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic(2→7)-disulfidato(3-)]-
Literature:
Villard L. et al. Cohort study of somatostatin-based radiopeptide therapy with [(90)Y-DOTA]-TOC versus [(90)Y-DOTA]-TOC plus [(177)Lu-DOTA]-TOC in neuroendocrine cancers. J. Clin. Oncol. 2012, 30, 1100-1106.
date of product catalogue issue: 10 May 2017

 
 
 

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