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ABX  advanced biochemical compounds   

Product Order number / Unit

9714 AMBA acetate 9714.0001: 1 mg per vial
9714.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.


Molar Mass: 1502.7
[721937-56-0] (net peptide)
Colourless to off-white freeze-dried solid packaged in screw cap vials.
Purity: ≥ 97 %
CoA; MS (identity); HPLC (purity)
Chemical Name:
Sequence: DOTA-Gly-4-Abz-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
DOTA = N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-
4-Abz = 4-aminobenzoyl
Supplied as acetate salt
CA index name: L-Methioninamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]glycyl-4-aminobenzoyl-L-glutaminyl-L-tryptophyl -L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-
Chen J. et al. Synthesis, stabilization and formulation of [177Lu]Lu-AMBA, a systemic radiotherapeutic agent for Gastrin Releasing Peptide receptor positive tumors. Appl Radiat Isot. 2008, 66, 497-505.
Waser B. et al. Selective in vitro targeting of GRP and NMB receptors in human tumours with the new bombesin tracer 177Lu-AMBA. Eur. J. Nucl. Med. Mol. Imaging. 2007, 34, 95-100.
Lantry L.E. et al. 177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer. J. Nucl. Med. 2006, 47, 1144-52.
Nunn A.D. et al. Preclinical evaluation of 177Lu-AMBA, a radiolabelled peptide for systemic radiotherapy and imaging of prostate cancer by targeting gastrin releasing peptide receptors. Eur. J. Cancer Suppl. 2004, 2, 89.
date of product catalogue issue: 24 February 2017


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