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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

9715 DOTA-[Pro1,Tyr4]bombesin (1-14) 9715.0001: 1 mg per vial
9715.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Precursor for radiolabelled DOTA-[Pro1,Tyr4]bombesin (1-14)
Molar Mass: 2042.28
C90H136N28O25S<
[593287-40-2] (net peptide)
Colourless to off-white freeze-dried solid packaged in screw cap vials.
Purity: ≥ 95 %
Certificates:
CoA; MS (identity); HPLC (purity)
Chemical Name:
Sequence: DOTA-Pro-Gln-Arg-Tyr-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
DOTA = [4,7,10-Tris-(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]-acetyl
Supplied as acetate salt
Synonymes:
Bombesin, 1-[1-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-L-proline]-4-L-tyrosine-; MP2346; DOTA-[P1, Y4]BBN(1-14); CA index name: Bombesin, 1-[1-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-L-proline]-4-L-tyrosine-
Literature:
Biddlecombe G.B. et al. Molecular Imaging of Gastrin-Releasing Peptide Receptor-Positive Tumors in Mice Using 64Cu- and 86Y-DOTA-[Pro1,Tyr4]-Bombesin(1-14). Bioconjug Chem. 2007, 18, 724-30.
Breeman W.A. et al. Evaluation of radiolabelled bombesin analogues for receptor-targeted scintigraphy and radiotherapy. Int J Cancer. 1999, 81, 658-65.
Breeman W.A. et al. Preclinical comparison of 111In-labeled DTPA- or DOTA-bombesin analogs for receptor targeted scintigraphy and radionuclide therapy. J. Nucl. Med. 2002, 43, 1650-56.
date of product catalogue issue: 24 February 2017

 
 
 

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