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ABX  advanced biochemical compounds   

Product Order number / Unit

9721 HYNIC-TOC trifluoroacetate 9720.0001: 1 mg per vial
9720.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

Precursor for [99mTc]HYNIC-TOC
Molar Mass: 1170.40
[257943-19-4] (net peptide)
Colourless to off-white freeze-dried solid packaged in screw cap vials.
Purity: ≥ 95 %
CoA; MS (identity); HPLC (purity)
Chemical Name:
Sequence: HYNIC-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide
HYNIC = residue of 6-Hydrazinopyridine-3-carboxylic acid
Supplied as trifluoroacetate salt
HYNIC-[Tyr3] Octreotide; CA index name: L-Cysteinamide, N-[(6-hydrazinyl-3-pyridinyl)carbonyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl- N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide
Decristoforo C. et al. 99mTc-EDDA/HYNIC-TOC: a new 99mTc-labelled radiopharmaceutical for imaging somatostatin receptor-positive tumours; first clinical results and intra-patient comparison with 111In-labelled octreotide derivatives. Eur. J. Nucl. Med. 2000, 27, 1318-1325.
Decristoforo C. et al. 99mTc-HYNIC-[Tyr3]-octreotide for imaging somatostatin-receptor-positive tumors: preclinical evaluation and comparison with 111In-octreotide. J. Nucl. Med. 2000, 41, 1114-1119.
Czepczynski, R. et al. Somatostatin receptor scintigraphy using 99mTc-EDDA/HYNIC-TOC in patients with medullary thyroid carcinoma. Eur J. Nucl. Med. Mol. Imaging. 2007, 34, 1635-45.
date of product catalogue issue: 10 May 2017


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