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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

9934 PSMA-617 (GMP)
Please inquire for customized filling and bulk quantities.

 
Precursor for [68Ga/177Lu/90Y]PSMA-617
PSMA: prostate-specific membrane antigen
Manufactured according to GMP requirements for APIs for use in clinical trials (ICH Q7 chapter 19)
Molar Mass: 1042.1 (net peptide)
C49H71N9O16
CAS-RN not yet assigned
Colourless to off-white solid
Purity: ≥ 98 %
Certificates:
CoA with ESI-MS and NMR (identity); HPLC (purity) ; GC (residual solvents); heavy metals content (ICP-MS); microbiology test
Chemical Name:
Synonymes:
2-[3-(1-Carboxy-5-{3-naphthalen-2-yl-2-[(4-{[2-(4,7,10-tris-carboxymethyl-1,4,7,10-tetraaza-cyclododec-1-yl)-acetylamino]-methyl}-cyclohexanecarbonyl)-amino]-propionylamino}-pentyl)-ureido]-pentanedioic acid
Literature:
Kratochwil C. et al. [177Lu]Lutetium-labelled PSMA ligand-induced remission in a patient with metastatic prostate cancer. Eur. J. Nucl. Med. Mol. Imaging. 2015, 42, 987-988.
Benesova M. et al. Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer. J. Nucl. Med. 2015, 56, 914-920.
date of product catalogue issue: 24 February 2017

 
 
 

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