Precursor for α-[¹¹C]Methyl-L-tryptophan
Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate
Pyrrolo[2,3-b]indole-1,2(2H)-dicarboxylic acid, 8-acetyl-3,3a,8,8a-tetrahydro-, 1,2-dimethyl ester, (2R,3aS,8aS)-rel-
Molar mass 318.32
CAS RN [79465-83-1]
Purity ≥ 95 %
- Colorless crystals
CoA: appearance, ¹H NMR spectrum
Shoaf S. et al. The suitability of [¹¹C]-α-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [¹¹C]- and [¹⁴C]-labeled tracer. J. Cereb. Blood Flow Metab. 2000, 20, 244–252.
Shoaf S. et al. Brain serotonin synthesis rates in rhesus monkeys determined by [¹¹C]-α-methyl-L-tryptophan and positron emission tomography compared to CSF 5-hydroxyindole-3-acetic acid concentrations. NeuroPsychopharmacology 1998, 19, 354–353.
Chakraborty P.K. et al. A high-yield and simplified procedure for the synthesis of α-[¹¹C]methyl-L-tryptophan. Nucl. Med. Biol. 1996, 23, 1005–1008.
Mzengeza S. et al. Asymmetric radiosynthesis of α-[¹¹C]methyl-L-tryptophan for PET studies. Nucl. Med. Biol. 1995, 22, 303–307.
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