CHEMICALS

UCB-J standard

Reference standard for [¹¹C]UCB-J

[¹¹C]UCB-J standard

(4R)-1-[(3-methyl-4-pyridyl)methyl]-4-(3,4,5-trifluorophenyl)pyrrolidin-2-one

Quality

Research Chemical

Characteristics

Molar mass 320.31

CAS RN [2242957-52-2]

Purity ≥ 95 %

  • colorless to off-white solid

Certificates

CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC

Literature

Nabulsi N. et al. Synthesis and Preclinical Evaluation of ¹¹C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J. Nucl. Med. 2016, 57, 777–784.

Mercier J. et al. Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands. Chem. Med. Chem. 2014, 9, 693–698.

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