Precursor for [¹¹C]diprenorphine and [¹⁸F]fluoroethyl-diprenorphine
CA index name: 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-6-hydroxy-α,α-dimethyl-3-(triphenylmethoxy)-, (5α, 7α)
Molar mass 653.87
CAS RN [157891-92-4]
Purity ≥ 95 %
- Colorless to yellowish solid
- soluble in chloroform, dimethyl sulfoxide, dimethylformamid, ethanol
CoA: appearance, ¹H and ¹³C NMR spectra (identity), MS (identity), HPLC (purity)
Luthra S.K. et al. Automated radiosyntheses of [6-O-methyl-¹¹C]-diprenorphine and [6-O-methyl-¹¹C]buprenorphine from 3-O-trityl protected precursors. Appl. Radiat. Isot. 1994, 45, 857–873.
Wester H.-J. et al. 6-O-(2-[¹⁸F]Fluoroethyl)-6-O-Desmethyl-diprenorphine ([¹⁸F]DPN): Synthesis, Biologic Evaluation, and Comparison with [¹¹C]DPN in Humans. J. Nucl. Med. 2000, 41, 1279–1286.
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