CHEMICALS

DFO*

Complexation agent for [⁸⁹Zr]-Labelling, immuno-PET

5,​11,​16,​22-​Tetraazahexacosanedi​amide, N¹-​[5-​(acetylhydroxyamino)​pentyl]​-​N²⁶-​(5-​aminopentyl)​-​N²⁶,​5,​16-​trihydroxy-​4,​12,​15,​23-​tetraoxo-

Quality

Research Chemical

Characteristics

Molar mass 760.92

CAS RN [1623757-38-9]

Purity ≥ 90 %

  • Colorless to off-white solid

Certificates

CoA: appearance, ¹H NMR spectrum (identity), ESI-MS (identity), HPLC (purity)

Literature

An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes. Chem. Commun., 2014, 50, 11523–11525.

Vugts et al. Comparison of the octadentate bifunctional chelator DFO*-pPhe-NCS and the clinically used hexadentate bifunctional chelator DFO-pPhe-NCS for ⁸⁹Zr-immuno-PET. Eur. J. Nucl. Med. Mol. Imaging. 2017, 44, 286–295.

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