Reference standard for impurity of DOTA-TATE acetate
[Tyr3]Octreotate trifluoracetate; TOCA; CA index name: L-Threonine, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide,
Sequence: H-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH, cyclic disulfide
Molar mass 1049.22
CAS RN [302794-43-0] (net peptide)
Purity ≥ 95 %
- Colorless freeze-dried solid
CoA: appearance, MS (identity), HPLC (purity)
Petrou C. et al. Synthesis and sst2 binding profiles of new (Tyr3)octreotate analogs. J.Peptide Sci. 2008, 14, 725–730.
Spyroulias G.A. et al. 3D solution structure of [Tyr3]octreotate derivatives in DMSO: Structure differentiation of peptide core due to chelate group attachment and biologically active conformation. Med. Chem. 2005, 1, 487–499.
Wang Q. et al. Pharmacological properties of hydrophilic and lipophilic derivatives of octreotate. Nucl. Med. Biol. 2004, 31, 21–30.
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