The norepinephrine transporter (NET) is a transmembrane protein involved in catecholamine uptake and is expressed in neuroendocrine tumors such as neuroblastoma. PET radiotracers like [¹⁸F]MFBG are commonly used as imaging agents to assess NET expression or monitor changes during research studies.Our latest addition to the ABX catalog is the MFBG-SPIAd precursor (ABX-Prod. No. 7038) with a spirocyclic iodonium ylide auxiliary. This precursor enables a straightforward, metal-free and two-step radiosynthesis of the [¹⁸F]MFBG radiotracer and thus represents an alternative to our current pinacol boronate MFBG-precursor (ABX-Prod. No. 7033, 7035).Both versions of the MFBG precursors and the reference standard (7034) are available for research and development purposes in selected countries worldwide. Place your quote request today:
ABX advanced biochemical compounds is a global frontrunner in radiopharmaceuticals, with a focus on positron emission tomography (PET) tracers. We develop and produce all compounds and components for any kind of radiotracer – from PET and SPECT precursors, PET reagent kits and cassettes, to complete radiopharmaceutical drug production in GMP environment.
Based in Radeberg, Germany, and founded in 1997, our team of about 400 employees is specialised in custom synthesis and manufacturing of precursors and peptides according to GMP for active pharmaceutical ingredients. Thanks to our expertise combined with bleeding edge equipment, we reach highest research, production, and quality standards.
ABX is the only service provider of radiopharmaceutical production with a complete and independent supply chain – from precursor or peptide to excipients and sterile disposables.
