Small molecules & peptides

3-Iodo-α-methyl-p-tyrosine

Reference standard for 3-[¹²³I]Iodo-α-methyl-L-tyrosine

L-3-Iodo-α-methyl-p-tyrosine; m-Iodo-α-methyl-L-tyrosine; 3-IMT; 3-IAMT

CA index name: L-Tyrosine, 3-iodo-α-methyl-

Quality

Research Chemical

Characteristics

Molar mass 321.11

CAS RN [4298-17-3]

Purity ≥ 95 % (HPLC)

  • Off-white solid

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Lahoutte T. et al. Increased Tumor Uptake of 3-¹²³I-Iodo-L-α-Methyltyrosine After Preloading with Amino Acids: An In Vivo Animal Imaging Study. J. Nucl. Med. 2002, 43, 1201–1206.

Weckesser M. et al. The role of L-3-I-123-iodine-a-methyl tyrosine -SPECT in cerebral gliomas. Nuklearmedizin 2000, 39, 233–240.

Stöcklin G. et al. Direct n.c.a. Electrophilic Radioiodination of Tyrosine Analogues, Their in vivo Stability and Brain-Uptake in Mice. Appl. Radiat. Isot. 1994, 45, 929–935.

Biersack H.J. et al. Imaging of Brain Tumors with L-3-[¹²³I]Iodo-α-Methyl Tyrosine and SPECT. J. Nucl. Med. 1989, 30, 110–112.

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