Small molecules & peptides

DOTA-Substance P

Precursor for radiometal-labelled neurokinin receptor targeted peptides

N2.1-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanyl-glycyl-L-leucyl-L-methionine amide

Sequence: DOTA-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂, supplied as acetate salt

Quality

Research Chemical

Characteristics

Molar mass 1734.0 (net peptide)

CAS RN [not yet assigned]

Purity ≥ 95 %

  • Colorless to off-white solid

Certificates

CoA: appearance, MS (identity), HPLC (purity)

Literature

De Araújo E.B. Radiolabeling of substance p with lutetium-177 and biodistribution study in rat pancreatic tumor xenografted nude mice. Cell. Mol. Biol. 2010, 56, 12–17.

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