Small molecules & peptides
SDM-8 tin precursor
Precursor for [¹⁸F]SDM-8
[¹⁸F]SDM-8 tin precursor; 2-Pyrrolidinone, 4-[3-fluoro-5-(trimethylstannyl)phenyl]-1-[(3-methyl-4-pyridinyl)methyl]-, (4R)-; SynVesT1 precursor
(R)-4-(3-fluoro-5-(trimethylstannyl)phenyl)-1-((3-methylpyridin-4-yl)methyl)pyrrolidin-2-one
Quality
Research Chemical
Characteristics
Molar mass 447.13
CAS RN [2289636-79-7]
Purity ≥ 95 %
- Colorless to yellowish oil or colorless to off-white solid
- soluble in dimethyl sulfoxide, dichloromethane, chloroform, ethyl acetate
Certificates
CoA: appearance, ¹H and ¹⁹F NMR spectra (identity), HPLC (purity)
Literature
Li S. et al. Synthesis and in Vivo Evaluation of a Novel PET Radiotracer for Imaging of Synaptic Vesicle Glycoprotein 2A (SV2A) in Nonhuman Primates. ACS Chem. Neurosci. 2019, 10, 1544–1554.
Li S. et al. ¹⁸F-SDM-8: A novel radiotracer for PET imaging of synaptic density. J. Nucl. Med. 2018, 59, supplement 1, 68.
Li S. et al. First-in-human Evaluation of ¹⁸F-SDM-8, A Novel Radiotracer for PET Imaging of Synaptic Vesicle Glycoprotein 2A. J. Nucl. Med. 2019, 60, supplement 1, 49.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/b65a8a37-56a2-46e6-807c-501b9a345f12 | Precursor | Product No.: 3425 |
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