Small molecules & peptides

UCB-J precursor

Precursor for [¹¹C]UCB-J

[¹¹C]UCB-J precursor

(R)-3-(Difluoroboranyl)-4-((2-oxo-4-(3,4,5-trifluorophenyl)pyrrolidin-1-l)methyl)-pyridin-1-ium fluoride


Research Chemical


Molar mass 374.09

CAS RN [not yet assigned]

Purity ≥ 97 %

  • colorless to off-white solid


CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC, chiral HPLC


Nabulsi N. et al. Synthesis and Preclinical Evaluation of ¹¹C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain. J. Nucl. Med. 2016, 57, 777–784.

Mercier J. et al. Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands. Chem. Med. Chem. 2014, 9, 693–698.

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