6-O-Tosyloxyethyl-CBT
Precursor for [¹⁸F]-labeling of N-terminal cysteine-bearing peptides and proteines
2-(2-cyanobenzothiazol-6-yloxy) 4-methylbenzenesulfonate; TE-CBT
CA index name: 2-Benzothiazolecarbonitrile, 6-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-
Quality
Research Chemical
Characteristics
Molar mass 374.44
CAS RN [1392498-16-6]
Purity ≥ 95 %
- Colorless to yellowish solid
Certificates
CoA: appearance, ¹H and ¹³C NMR spectra
Literature
Ren H. et al. A biocompatible condensation reaction for the labeling of terminal cysteine residues on proteins.Angew. Chem. Int. Ed. 2009, 48, 9658–9662.
Jeon J. et al. Efficient method for site-specific ¹⁸F-labeling of bioMolecules using the rapid condensation reaction between 2-cyanobenzothiazole and cysteine. Bioconjugate Chem. 2012 , 23, 1902 – 1908.
Godinat A. et al. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem. Biol. 2013, 8, 987–999.
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Product | Product No. | Filling amount | Quantity | ||
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/products/small-molecules-and-peptides/chemical/115652d5-af3d-4016-b6db-6b2d0aa6354c | Precursor | Product No.: 5149 | Filling amount: 2 mg | ||
/products/small-molecules-and-peptides/chemical/115652d5-af3d-4016-b6db-6b2d0aa6354c | Precursor | Product No.: 5149 |