Small molecules & peptides

Anhydrothymidine-FLT precursor

Precursor for [¹⁸F]FLT (3'-deoxy-3'-[¹⁸F]fluorothymidine)

5'-O-(4,4'-dimethoxytrityl)-2,3'-anhydrothymidine; 2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one, 3-[4,4'-dimethoxtrityl]-2,3-dihydro-8-methyl-, (2R,3R,5R)-; (2R,3R,5R)-3-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3-dihydro-8-methyl- 2,5-methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one

CA index name: 2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one, 3-[4,4'-dimethoxtrityl]-2,3-dihydro-8-methyl-, (2R,3R,5R)-

Quality

Research Chemical

Characteristics

Molar mass 526.58

CAS RN [191474-13-2]

Purity ≥ 95 %

  • Colorless to yellowish solid

Certificates

CoA: appearance, ¹H NMR spectrum, HPLC

Literature

Machulla H.J. et al. Simplified labelling approach for synthesizing 3'-deoxy-3'-[¹⁸F]fluorothymidine ([¹⁸F]FLT). J. Radioanl. Nucl. Chem. 2000, 243, 843–846.

Eisenhut M. et al. Synthesis of 3'-deoxy-3'-[¹⁸F]fluorothymidine with 2,3'-anhydro-5'-O-(4,4'-dimethoxytrityl)-thymidine. J. Labelled Compd. Radiopharm. 2000, 43, 1211–1218.

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Product No.: 1210Filling amount: 10 mg
Product No.: 1210

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