Small molecules & peptides

PBR06 standard

Reference standard for [¹⁸F]PBR06 and [¹¹C]PBR06

N-(2,5-Dimethoxy-benzyl)-2-fluoro-N-(2-phenoxy-phenyl)-acetamide; Acetamide, N-[(2,5-dimethoxyphenyl)methyl]-2-fluoro-N-(2-phenoxyphenyl)-

2-Fluoro-N-(2-methoxy-5-methoxybenzyl)-N-(2-phenoxyphenyl)acetamide

Quality

Research Chemical

Characteristics

Molar mass 395.42

CAS RN [1104493-11-9]

Purity ≥ 95 %

  • colorless to milky yellowish oil
  • soluble in dimethyl sulfoxide, chloroform, ethyl acetate

Certificates

CoA: appearance, ¹H and ¹⁹F-NMR spectra, HPLC (Purity)

Literature

Imaizumi M. et al. Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain. Synapse 2007, 61, 595–605.

Briard E. et al. Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive ¹⁸F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET. J. Med. Chem. 2009, 52, 688–699.

Wang M. et al. Synthesis of [¹¹C]PBR06 and [¹⁸F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO). Steroids 2011, 76, 1331–1340.

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Product No.: 1672

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