FFNP precursor
Precursor for [¹⁸F]FFNP ([¹⁸F]fluoro furanyl norprogesterone)
16α,17α-[(R)-(1'-α-Furylmethylidene)dioxy]-21[(methyl)sulfonyl]oxy-19-norpregn-4-ene-3,20-dione; [¹⁸F]FFNP precursor
CA index name: 19-Norpregn-4-ene-3,20-dione, 16,17-[[(R)-2-furanylmethylene]bis(oxy)]-21-[(methylsulfonyl)oxy]-, (16α)-
Quality
Research Chemical
Characteristics
Molar mass 504.59
CAS RN [445379-33-9]
Purity ≥ 95 %
- Colorless to off-white solid
Certificates
CoA: appearance, ¹H NMR spectrum
Literature
Zhou D. et al. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16α-[¹⁸F]fluoroestradiol (FES), [¹⁸F]fluoro furanylnorprogesterone (FFNP), and 16β-[¹⁸F]fluoro-5α-dihydrotestosterone (FDHT) as radiopharmaceuticals. J. Label. Compd. Radiopharm. 2014, 5, 371–377.
Vijaykumar D. et al. An Efficient Route for the Preparation of a 21-Fluoro Progestin-16α,17α-Dioxolane, a High-Affinity Ligand for PET Imaging of the Progesterone Receptor. J. Org. Chem. 2002, 67, 4904–4910.
Buckman B.O. et al. Fluorine-18-Labeled Progestin 16α,17α-Dioxolanes: Development of High-Affinity Ligands for the Progesterone Receptor with High in Vivo Target Site Selectivity. J. Med. Chem. 1995, 38, 328–337.
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Product | Product No. | Filling amount | Quantity | ||
---|---|---|---|---|---|
/products/small-molecules-and-peptides/chemical/1ae5459b-275b-48d0-8679-748234e6644a | Precursor | Product No.: 1926 | Filling amount: 2 mg | ||
/products/small-molecules-and-peptides/chemical/1ae5459b-275b-48d0-8679-748234e6644a | Precursor | Product No.: 1926 | Filling amount: 10 mg | ||
/products/small-molecules-and-peptides/chemical/1ae5459b-275b-48d0-8679-748234e6644a | Precursor | Product No.: 1926 |