Small molecules & peptides

FFNP precursor

Precursor for [¹⁸F]FFNP ([¹⁸F]fluoro furanyl norprogesterone)

16α,17α-[(R)-(1'-α-Furylmethylidene)dioxy]-21[(methyl)sulfonyl]oxy-19-norpregn-4-ene-3,20-dione; [¹⁸F]FFNP precursor

CA index name: 19-Norpregn-4-ene-3,20-dione, 16,17-[[(R)-2-furanylmethylene]bis(oxy)]-21-[(methylsulfonyl)oxy]-, (16α)-


Research Chemical


Molar mass 504.59

CAS RN [445379-33-9]

Purity ≥ 95 %

  • Colorless to off-white solid


CoA: appearance, ¹H NMR spectrum


Zhou D. et al. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16α-[¹⁸F]fluoroestradiol (FES), [¹⁸F]fluoro furanylnorprogesterone (FFNP), and 16β-[¹⁸F]fluoro-5α-dihydrotestosterone (FDHT) as radiopharmaceuticals. J. Label. Compd. Radiopharm. 2014, 5, 371–377.

Vijaykumar D. et al. An Efficient Route for the Preparation of a 21-Fluoro Progestin-16α,17α-Dioxolane, a High-Affinity Ligand for PET Imaging of the Progesterone Receptor. J. Org. Chem. 2002, 67, 4904–4910.

Buckman B.O. et al. Fluorine-18-Labeled Progestin 16α,17α-Dioxolanes: Development of High-Affinity Ligands for the Progesterone Receptor with High in Vivo Target Site Selectivity. J. Med. Chem. 1995, 38, 328–337.

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Product No.: 1926Filling amount: 2 mg
Product No.: 1926Filling amount: 10 mg
Product No.: 1926

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