Small molecules & peptides

SB206453 (GMP)

Precursor for [¹¹C]SB207145

8-Amino-7-chloro-2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid piperidin-4-ylmethyl ester; 8-Amino-7-chloro-(4-piperidylmethyl)-1,4-benzodioxan-5-carboxylate; [¹¹C]SB207145 precursor

CA index name: 1,4-Benzodioxin-5-carboxylic acid, 8-amino-7-chloro-2,3-dihydro-, 4-piperidinylmethyl ester


GMP Product


Molar mass 326.78

CAS RN [148702-73-2]

Purity ≥ 97 %

  • Colorless to yellowish solid
  • Tested for bioburden and bacterial endotoxins.


CoA: appearance, NMR and IR spectra, melting point (identity), HPLC (purity), GC (residual solvents), microbiology test


Gee A.D. et al. Synthesis and evaluation of [¹¹C]SB207145 as the first in vivo serotonin 5-HT₄ receptor radioligand for PET imaging in man. Curr. Radiopharm. 2008, 1, 110–114.

Marner L. et al. Kinetic modeling of ¹¹C-SB207145 binding to 5-HT₄ receptors in the human brain in vivo. J. Nucl. Med. 2009, 50, 900–908.

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Product No.: 1881Filling amount: 50 mg
Product No.: 1881

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