Small molecules & peptides
(R)-N-Desmethyl PK11195
Precursor for (R)-[N-Methyl-¹¹C-]PK11195
1-(2-Chlorophenyl)-N-(1-methylpropyl)-isoquinoline-3-carboxamide
CA index name: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-(1-methylpropyl),-(R)
Quality
Research Chemical
Characteristics
Molar mass 338.83
CAS RN [157809-85-3]
Purity ≥ 99 % (HPLC)
- Colorless crystals
Certificates
CoA: appearance, ¹H NMR spectrum, HPLC
Literature
Camsonne R. et al. Synthesis of N-[¹¹C]methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1-isoquinoline carboxamide-3 (PK11195): a new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985–991.
Hashimoto K. et al. Synthesis and evaluation of ¹¹C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63–71.
Shah F. et al. Synthesis of the Enantiomers of [N-methyl-¹¹C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573–581.
Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl-¹¹C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Int. J. Rad. Appl. Instrum. B, 1992, 19, 159–166.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/3412e11f-0f0c-45d3-a625-d75a57215469 | Precursor | Product No.: 1600 | Filling amount: 1 mg | ||
| /products/small-molecules-and-peptides/chemical/3412e11f-0f0c-45d3-a625-d75a57215469 | Precursor | Product No.: 1600 | Filling amount: 2 mg | ||
| /products/small-molecules-and-peptides/chemical/3412e11f-0f0c-45d3-a625-d75a57215469 | Precursor | Product No.: 1600 |
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