Small molecules & peptides
O-Desmethyl Astemizole
Precursor for [¹¹C]Astemizole and [¹⁸F]Fluoroethyl-astemizole
O-desmethylastemizole; 4-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-ylamino]-piperidin-1-yl}-ethyl)-phenol; [¹¹C]Astemizole precursor; [¹⁸F]Astemizole precursor
4-[2-[4-[[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]phenol
Quality
Research Chemical
Characteristics
Molar mass 444.54
CAS RN [73736-50-2]
Purity ≥ 95 %
- Colorless to off-white solid
Certificates
CoA: appearance, ¹H and ¹⁹F NMR spectra
Literature
Riss P.J. et al. Radiosynthesis and characterization of astemizole derivatives as lead compounds toward PET imaging of τ-pathology. Med. Chem. Commun. 2013, 4, 852–855.
Cai L. et al. Synthesis of [¹¹C]astemizole as a lead candidate radioligand for imaging brain neurofibrillary tangles. Neuroimage 2010, 52, Supplement 1, S152-S153.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/392c99ff-3041-4a19-ab62-a271c0e8cb4d | Precursor | Product No.: 5166 |
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