Small molecules & peptides

Iodo-Darolutamide

Precursor for [¹¹C]Darolutamide

[¹¹C]Darolutamide precursor

N-((S)-1-(3-(3-chloro-4-iodophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide

Quality

Research Chemical

Characteristics

Molar mass 499,74

CAS RN [not yet assigned]

Purity ≥ 95 % (HPLC)

  • Colorless to off-white solid
  • soluble in dimethyl sulfoxide

Certificates

CoA: appearance, ¹H NMR spectrum (identity), HPLC (purity)

Literature

Hughes D.L et al. Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide. Org. Process Res. Dev. 2020, 24, 347−362.

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