Small molecules & peptides

Tosyl-propargyl-diethylene glycol

Precursor for [¹⁸F]Fluoro-propargyl-diethylene glycol

TPDG; Toluene-4-sulfonic acid 2-(2-prop-2-ynyloxy-ethoxy)-ethyl ester

CA index name: Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate)


Research Chemical


Molar mass 298.36

CAS RN [1119249-30-7]

Purity ≥ 95 %

  • Colorless to yellowish oil


CoA: appearance, ¹H NMR spectrum


Sirion U. et al. An efficient F-18 labeling method for PET study: Huisgen 1,3-dipolar cycloaddition of bioactive substances and F-18-labeled compounds. Tetrahedron Lett. 2007, 48, 3953–3957.

Li Z.-B. et al. Click Chemistry for ¹⁸F-Labeling of RGD Peptides and microPET Imaging of Tumor Integrin ανβ3 Expression. Bioconjugate Chem. 2007, 18, 1987–1994.

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