Small molecules & peptides

TetraBoc-L-DOPA methyl ester

Stannylated precursor for nucleophilic radiosynthesis of 6-[¹⁸F]Fluoro-L-DOPA

Boc₄DOPA(2-SnMe₃) methyl ester; N,N-di-tert-butoxycarbonyl-3,4-di-tert-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine methyl ester

CA index name: L-Tyrosine, N,N,O-tris[(1,1-dimethylethoxy)carbonyl]-5-[[(1,1-dimethylethoxy)carbonyl]oxy]-2-(trimethylstannyl)-, methyl ester


Research Chemical


Molar mass 774.48

CAS RN [2015236-76-5]

Purity ≥ 95 %

  • colorless solid to yellowish oil
  • soluble in ethyl acetate, dichloromethane, chloroform, diehtyl ether


CoA: appearance, ¹H and 119Sn NMR spectra, HPLC


Makaravage K. J. et al. Copper-Mediated Radiofluorination of Arylstannanes with [¹⁸F]KF. Org. Lett.2016, 18, 5440–5443.

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