Small molecules & peptides


Reference standard for [¹⁸F]FE-PEO


CA index name: 6,14-Ethenomorphinan-7-methanol, -4,5-epoxy-6-(2-fluoroethoxy)-α,17-dimethyl-,α-(2-phenylethyl)-3-(triphenylmethoxy)-, (5α, 7α)


Research Chemical


Molar mass 505.62

CAS RN [not yet assigned]

Purity ≥ 95 %

  • Colorless to yellowish solid


CoA: appearance, ¹H, ¹³C and ¹⁹F NMR spectra


Marton J. et al. Design and synthesis of an ¹⁸F-labeled version of phenethyl-orvinol ([¹⁸F]FE-PEO) for PET-imaging of opioid receptors. Molecules 2012, 17, 11554–11569.

Riss P.J. et al. Syntheis and evaluation of ¹⁸F-FE-PEO in rodents: An ¹⁸F-labeled full agonist for opioid receptor imaging. J. Nucl. Med. 2013, 54, 299–305.

Schoultz, B. W. et al. Synthesis and evaluation of three structurally related ¹⁸F-labeled orvinols of different intrinsic activities: [¹⁸F]fluoroethyl-diprenorphine ([¹⁸F]FDPN), [¹⁸F]fluoroethyl-buprenorphine ([¹⁸F]FBPN and [¹⁸F]fluoroethyl-phenethyl-orvinol ([¹⁸F]FPEO. J. Med. Chem. 2014, 57, 5464–5469.

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