Small molecules & peptides

2-Bromoethyl triflate

Precursor for [¹⁸F]BFE (1-bromo-2-[¹⁸F]fluoroethane)

Trifluoromethanesulfonic acid 2-bromoethyl ester

CA index name: Methanesulfonic acid, 1,1,1-trifluoro-, 2-bromoethyl ester; Methanesulfonic acid, trifluoro-, 2-bromoethyl ester


Research Chemical


Molar mass 257.03

CAS RN [103935-47-3]

Purity ≥ 95 %

  • colorless to slightly colored liquid


CoA: appearance, ¹H and ¹⁹F NMR spectra


Wang J.-Q. et al. Synthesis and preliminary biological evaluation of O⁶-[4-(2-[¹⁸F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O⁶-alkylguanine-DNA alkyltransferase in cancer chemotherapy. Bioorg. Med. Chem. 2005, 13, 5779–5786.

Lin K.-S. et al. Synthesis, enantiomeric resolution, F-18 labeling and biodistribution of reboxetine analogs: promising radioligands for imaging the norepinephrine transporter with positron emission tomography. Nucl. Med. Biol. 2005, 32, 415–422.

Chi D.Y. et al. A rapid and efficient method for the fluoroalkylation of amines and amides. Development of a method suitable for incorporation of the shortlived positron emitting radionuclide fluorine-18. J. Org. Chem. 1987, 52, 658- 664.

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