Small molecules & peptides

MK-9470 precursor

Precursor for [¹⁸F]MK-9470

Propanamide, N-[(1S,2S)-2-(3- cyanophenyl)-1-methyl-3-[4-[2-[[(4-methylphenyl)sulfonyl]oxy] ethoxy]phenyl]propyl]-2-methyl-2-[(5-methyl-2-pyridinyl)oxy] -; [¹⁸F]MK-9470 precursor; [¹⁸F]MK-9470 tosylate precursor

2-(4-((2S,3S)-2-(3-cyanophenyl)-3-(2-methyl-2-(5-methylpyridin-2-yloxy)propanamido)butyl)phenoxy)ethyl 4-methylbenzenesulfonate


Research Chemical


Molar mass 641.78

CAS RN [1646148-10-8]

Purity ≥ 95 %

  • Colorless to off-white solid
  • soluble in dimethyl sulfoxide, chloroform, methanol, ethyl acetate


CoA: appearance, ¹H NMR spectrum (identity), HPLC (purity)


Thomae D. et al. Automated one-step radiosynthesis of the CB1 receptor imaging agent [¹⁸F]MK-9470. J. Labelled Compd. Radiopharm. 2014, 57, 611–614.

Liu P. et al. Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[¹⁸F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin- 2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use. J. Med. Chem. 2007, 50, 3427–3430.

Burns H.D. et al. [¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. PNAS 2007, 104, 9800–9805.

Emonds K.M. et al. ¹⁸F-MK-9470 PET imaging of the type 1 cannabinoid receptor in prostate carcinoma: a pilot study. EJNMMI Research 2013, 3, 59.

Add to inquiry

Product No.Filling amountQuantity
Product No.: 5650

Related products

Product was added