Small molecules & peptides

DOTA-TATE acetate

Precursor for radiolabelled DOTA-[Tyr³]octreotate

DOTA-[Tyr3]-Octreotate, DOTA-[Tyr3, Thr8]-Octreotide

DOTA-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH, cyclic disulfide; DOTA = N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-; Supplied as acetate salt

Quality

Research Chemical

Characteristics

Molar mass 1435.63

CAS RN [177943-89-4]

Purity ≥ 97 %

  • Colorless to off-white freeze-dried solid

Certificates

CoA: appearance, MS (identity), HPLC (purity)

Literature

De Jong M. et al. Combination Radionuclide Therapy Using ¹⁷⁷Lu- and ⁹⁰Y-Labeled Somatostatin Analogs. J. Nucl. Med., 2005, 46,13S.

Valkema R. et al. Long-Term Follow-Up of Renal Function After Peptide Receptor Radiation Therapy with ⁹⁰Y-DOTA⁰,Tyr³-Octreotide and ¹⁷⁷Lu-DOTA⁰,Tyr³-Octreotate. J. Nucl. Med. 2005, 46, 8.

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