Small molecules & peptides

FDHT precursor

Precursor for [¹⁸F]FDHT (16β-[¹⁸F]fluoro-5α-dihydrotestosterone)

16α-[[(trifluoromethyl)sulfonyl]oxy]-3,3-(ethylenedioxy)androstan-17-one; [¹⁸F]FDHT precursor

CA index name: Androstane-3,17-dione, 16-[[(trifluoromethyl)sulfonyl]oxy]-, cyclic 3-(1,2-ethanediyl acetal), (5α,16α)-


Research Chemical


Molar mass 480.54

CAS RN [141664-05-3]

Purity ≥ 95 %

  • Colorless to off-white solid


CoA: appearance, ¹H NMR spectrum

Product sheets (PDF)


Liu A. et al. Fluorine-18-Labeled Androgens: Radiochemical Synthesis and Tissue Distribution Studies on Six fluorine-Substituted Androgens, Potential Imaging Agents for Prostatic Cancer. J. Nucl. Med. 1992, 33, 724–734.

Zhou D. et al. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16α-[¹⁸F]fluoroestradiol (FES), [¹⁸F]fluoro furanylnorprogesterone (FFNP), and 16β-[¹⁸F]fluoro-5α-dihydrotestosterone (FDHT)as radiopharmaceuticals. J. Label. Compd. Radiopharm. 2014, 5, 371–377 DOI: 10.1002/jlcr.3191

Dehdashti F. et al. Positron tomographic assessment of androgen receptors in prostatic carcinoma. Eur. J. Nucl. Med. Mol. Imaging 2005, 32, 344–350.

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