Small molecules & peptides

HYNIC-cyclo(RGDfK) dimer trifluoroacetate

Precursor for αvβ3 integrin targeted, ⁹⁹mTc-labelled RGD-peptides

CA index name: Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl), 5,5'-[N-[(6-hydrazino-3-pyridinyl)carbonyl]-L-glutamoyl]bis-

Sequence: Hynic-cyclo(-Arg-Gly-Asp-D-Phe-Lys-) dimer


Research Chemical


Molar mass 1453.6 (net peptide)

CAS RN [500166-11-0]

Purity ≥ 95 %

  • Colorless to off-white solid


CoA: appearance, MS (identity), HPLC (purity)


Jia B. et al. ⁹⁹mTc-Labeled Cyclic RGDfK Dimer: Initial Evaluation for SPECT Imaging of Glioma Integrin ανβ3 Expression. Bioconjugate Chem. 2006, 17, 1069–1076.

Janssen M.L. et al. Tumor Targeting with Radiolabeled ανβ3 Integrin Binding Peptides in a Nude Mouse Model. Cancer Res.2002, 62, 6146–6151.

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