Small molecules & peptides


Precursor for [¹¹C]CGP 12177

CA index name: 2-Propanol, 1-(2-amino-3-nitrophenoxy)-3-[(1,1-dimethylethyl)amino]-, (S)-


Research Chemical


Molar mass 283.32

CAS RN [132059-12-2]

Purity ≥ 95 %

  • Yellowish solid


CoA: appearance, ¹H and ¹³C NMR spectra


Hammadi A. et al. Asymmetric synthesis of (2S)-and (2R)-4-(3-tert-butylamino-2-hydroxypropoxy)benzimidazol-2-[¹¹C]-one ((S)-and (R)-[¹¹C]-CGP 12177) from optically active precursors J. Labelled Compd. Radiopharm. 1991, 29, 681–690.

Merlet P. et al. Positron emission tomography with ¹¹C CGP-12177 to assess β-adrenergic receptor concentration in idiopathic dilated cardiomyopathy. Circulation 1993, 87, 1169–1178.

Nishijima K. et al. Preparation and pharmaceutical evaluation for clinical application of high specific activity S-(–)-[¹¹C]CGP-12177, a radioligand for [β]-adrenoreceptors. Nucl. Med. Commun. 2004, 25, 845–849.

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